الفهرس | Only 14 pages are availabe for public view |
Abstract The current study was carried out to evaluate and compare the level of receptor activator of nuclear factor KB ligand (RANKL) and osteoprotegerin (OPG) and its ratio (RANKL/OPG ratio) in saliva and Gingival Crevicular Fluid (GCF) of patients with chronic periodontitis and clinically healthy individuals. Ninety subjects were selected from the outpatient Clinic, Faculty of Dentistry, Tanta University for this case-control, cross sectional study. Their ages ranged between 30 to 60 years old. All subjects were interviewed to obtain medical and demographic information and were given a clinical screening for oral pathology and periodontal examination. The information that was gathered included the subject’s gender, age and smoking habit. The study was approved by the ethical committee of faculty of dentistry, Tanta University and they gave their informed consent as all procedures were explained before the beginning of the study. All subjects were divided into two groups: group 1: Forty five subjects with clinically healthy gingiva were recruited from the faculty, staff and student of the faculty as a control group. group 2: Forty five patients with moderate to severe chronic periodontitis based on the criteria defined by the American Academy of Periodontology. |