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العنوان
Evaluation of MicroRNA-93 and miRNA-210 in Egyptian Patient with Post HCV Hepatocellular Carcinoma /
المؤلف
El said,Mai Mohamed .
هيئة الاعداد
باحث / مي محمد السيد محمد
مشرف / أمال تهامي عبد المعز
مشرف / محمد صلاح الدين
مشرف / نشوي ناجي الخزرجي
تاريخ النشر
2017.
عدد الصفحات
252.p;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب (متفرقات)
تاريخ الإجازة
1/10/2017
مكان الإجازة
جامعة عين شمس - كلية الطب - Tropical Medicine
الفهرس
Only 14 pages are availabe for public view

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from 251

Abstract

High sensitivity and specificity was found in both miR-210 and miR-93a to distinguish between HCC and control group, the sensitivity for the miR-210 and miR-93a was 97%, 99% respectively and the specificity was 99.5%, 93%; respectively.
Also the studied miRNAs showed reasonable sensitivity and specificity to distinguish between BCLC-A /BCLC-Non A, The sensitivity for the miR-210 and miR-93a were 60%, 60% and the specificity 93%, 80%; respectively.
Furthermore we found positive correlation between genetic expression of miRNA 210, 93a and adjacent lymph node enlargement (p=0.000) and with BCLC staging (p=0.000).
As regard correlation between miRNA 210, miRNA 93a and liver function parameters, our results showed that there were no significant correlation between increased expression of miRNA93, 210 liver parameters (albumin, bilirubin, AST, ALT).