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العنوان
Vasculitis in thyrotoxicosis
Is it drug induced or disease related? /
المؤلف
Khatab, Doaa Mahmoud Hamed.
هيئة الاعداد
باحث / دعاء محمود حامد خطاب
مشرف / ماهر أبوبكر الأمـــيـر
مشرف / نجوى كمال الدين رشدى
مناقش / مصطفى حسن طه
مناقش / محمد عبد الهادى مشاحيت
الموضوع
Vasculopathie.
تاريخ النشر
2015.
عدد الصفحات
143 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب
تاريخ الإجازة
25/3/2015
مكان الإجازة
جامعة الفيوم - كلية الطب - قسم الأمراض الباطنة
الفهرس
Only 14 pages are availabe for public view

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from 141

Abstract

In the last few years, there was an increased incidence of vasculitis in
patients with thyrotoxicosis. Those vasculitic reactions ranged from simple
purpuric skin lesion to sever intra-alveolar hemorrhage and even to Steven
Johnson Syndrome (SJS). Most of those vasculitic reactions occurred in
patients receiving propylthiouracil or methimazole (Noh et al.,
2009 ).However, many other cases were detected in thyrotoxic patients not
receiving those medications(Lee et al., 2007 ).
In our study MPO-ANCA (p-ANCA)levels in plasma are evaluated as an
indicator of vasculitis in 100 male and female thyrotoxic patients,25
Grave’s on treatment, 25 Grave’s on no treatment,25 thyrotoxic (nodular or
multinodular) on treatment,25thyrotoxic (solitary nodular or multinodular)
on no treatment, and a control group of 25 healthy subjects. All patients
were subjected to detailed clinical examination and investigations which
included CBC,T3, T4, TSH, CBC, ESR, ALT, AST, urine analysis, p-
ANCAand anti-thyroglobulin antibodies.