الفهرس 
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Abstract
Diffusion weighted MR imaging as a globally spreading non-invasive diagnostic modality that has proven its reliability in solving various imaging challenges throughout different body systems can also be beneficial in staging and grading of bladder cancer to guide treatment thus avoiding the risks of the more invasive procedures such as cystoscopic guided biopsy. This study was conducted to evaluate the role of diffusion-weighted MR imaging with apparent diffusion coefficient (ADC) values and its relationshipto the histo-pathological characteristics of bladder cancers. Diffusion-weighted MR imagingusing a 1.5 Tesla imager with a b-value of 800 s/mm2has beenperformed before transurethral (TUR) resection of 50 bladder cancercases. ADC values wereobtained and their relationshipstohistopathological characteristicssuch as T stage and tumor grade were analyzed. The mean ADC value was significantly lower in invasive tumors (Stage T2 or higher)than in superficial non-invasive tumors (Stage T1 or lower)(P < 0.001). Receiver operating characteristic curve has estimated the accuracy of detection of muscle invasive bladder cancers by using area under curve (AUC), showing 86%. The mean ADC value of urothelial tumors depicted at diffusion-weighted MR imaging was significantly lower in Grade 3 than in Grade 1 (P = 0.002) and lower in Grade 2 than in Grade 1 (P = 0.003) with accuracy of 94.4% and 90% respectively, according to receiver operating characteristic curve by using area under curve (AUC).