الفهرس 
The Use of an Intermediate Layer in HypospadiasOnly 14 pages are availabe for public view
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Abstract
Abstract
• Objective: To compare Snodgrass operation (tubularized incised plate (TIP) urethroplasty) with fibrin glue application & Snodgrass operation with dorsal dartos flap as an intermediate layer.
• Study design: A prospective randomized clinical trial
• Study setting: The study was conducted at Pediatric Surgery Department, Ain Shams University Hospitals.
• Patients: This clinical trial included 60 patients with hypospadias in which Snodgrass operation was performed. Patients were divided into 2 groups, each included 30 patients, group A in which fibrin glue (FibroglooTM) was applied & group B in which a dorsal dartos flap was used as an intermediate layer.
• Results: Fistula occurred in 11 cases in the fibrin glue group (37.9 %) and 6 cases in the dorsal dartos flap group (20.7%) (p value = 0.248). Dehiscence occurred in 7 cases (24.1 %) in both the fibrin glue and dorsal dartos flap groups (p value = 1.000). Meatal stenosis occurred in 4 cases in the fibrin glue group (13.8%) and 5 cases in the dorsal dartos flap group (17.2%) (p value = 1.000). One patient in the fibrin glue group had meatal synaechia (3.4%) (p value = 1.000).
• Conclusion: The study showed no statistical significance between the 2 groups as regards the incidence of fistula, meatal stenosis or dehiscence, although there was a trend for increased fistula formation in case of fibrin glue.
Key words: fibrin glue, dorsal dartos flap, Snodgrass operation