الفهرس 
Histology of the choroidOnly 14 pages are availabe for public view
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Abstract
Purpose: comparison of effect of different types of injections (PSTA, IVTA, and IVB) on choroidal thickness in patients with diffuse diabetic macular edema.
Methods: changes in the subfoveal choroidal thickness, central macular thickness and best corrected visual acuity are studied in 30 eyes with diffuse diabetic macular edema. 30 eyes are divided into three groups, each group with 10 eyes is injected with IVTA, and IVB or STA. changes are studied after 2 and 4 weeks of injection.
Results: the baseline mean SFCT showed no significant change (P>0.05). after 4 weeks of injection in any of the three groups. The mean CMT was 505.2 ±142.7 µm, 435.4± 39.5 µm, and 494.4 ±145.2µm in group I(IVTA), II (IVB)and III(STA) respectively which decreased significantly after 4 weeks of injection to 362.9 ± 53.2µ(P=0.02) , 375.6 ±61.5 µ (P=0.001) 471.2± 147.1µ (P=0.007), respectively. The mean baseline BCVA was 0.85 ±0.2 logMAR units in the IVTA group, 0.86±0.4 logMAR units in the IVB group and 0.79±0.2 logMAR units in the STA group which significantly improved in group I (IVTA) to 0.49± 0.1 logMAR units (p=0.001) with no significant improvement in group II (IVB) to 0.64 ± 0.4 logMAR units (P=0.05) and no significant improvement in group III (STA) to 0.71 ± 0.2 log MAR units (P=0.05).
Conclusion: SFCT is thinner in eyes with DME. Best macular anatomical and visual outcomes were associated with IVTA injection then IVB injection and least improvement with STA injection. However no correlation is found between the SFCT and macular thickness so that initial SFCT cannot be a biomarker for DME progression or for response to treatment.