الفهرس 
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Abstract
Management of difficult airway continues to be an anesthetic challenge. Multiple algorithms have been defined for this issue. Awake intubation is often the safe way and the gold standard for management of patients with known or suspected difficult airways. The main goal of conscious sedation is to have an awake, calm,cooperative patient who can follow verbal commands while maintaining adequate oxygenation and ventilation. Many agents are used for sedation including benzodiazepines, opioids,ketamine,propofol, and dexmedetomidine.This prospective randomized double blind study compared between dexmedetomidine and propofol for conscious sedation during awake LMA-CTrach intubation in patients with anticipated difficult airway. Itwas carried out in Oncology Center, Mansoura University(OCMU)on40patients of either sex with age ranging from 18 to 65 years old with anticipated difficult airway(TAS more than 6).Patients were classified, according to the type of sedative drug used into two groups, Group1(Dexmedetomidine group; D group),Group2(Propofol group; P group).Data regarding Thetime taken to achieve sedation (RSS = 2)(T1),insertion time(T2),intubation time(T3), number of attempts of CTrach insertion and 5-point scale of the initial view were collected. Blood pressure, HR, and peripheral oxygen saturation(SpO2) were recorded before starting drug infusion(base line)and every minute until tracheal intubation. Hypoxic episodes(SpO2< 90 %),patients’ recall, side effects (sore throat and hoarseness of voice)and satisfaction score were assessed.from this study ,we can conclude that dexmedetomidine is better than propofol when used for conscious sedation during awake LMA-CTrach intubation in patients with anticipated difficult airway as Dexmedetomidine appeared to offer better patient tolerance, better preservation of a patent airway, better analgesia,and less effect on hemodynamic variables, in comparison to propofol.