الفهرس | Only 14 pages are availabe for public view |
Abstract The lymphatic system is affected in many general diseases for example T.B, Septic diseases, and leukaemia. Enlargement of the cervical lymph nodes is commonly seen in children. In most instances they represent transient response to a benign local or generalised infection. However, it is always important to differentiate between the benign lymphoid hyperplasia and the lymph node enlargement due to serious conditions such as leukaemia or lymphoma. This research concentrated on cervical lymphadensopathy due to infestation with lice which is one of the most common local infections that are usually accompanied with cervical lyn1phadenopathy. These ectoparasites are still one of the most common public health problems in Egypt. This is particulary true among school students who are exposed to parasitic infestations by contagious infection and then convery the parasites to their family membres. The association of lymphadenopathy and parasite infestation is explained by the fact that lymph nodes are stimulated as part of an immune response evoked by the parasite. This may suggest a new aetiological factor for the enlargement of lymph nodes other than malignancyin Egyptian children. The aim of this work was to study the presence of specific immunoglobulins against pediculosis in the serun1 of children with cervical lymphadenopathy. Two groups of children were exan1ined group I: Twenty patien ts infested with pediculus hun1anus capitis, (8 males and 12 fen1ales,), their ages ranged fron1(6-11years). group II: Eight non infested children (4 males and 4 fan1ales) with matching ages were selected as controls. Data of the presen t study showed that lice infestation (head lice) is one of the causes of ly1nphadenopa thy (cervical and/or occipital) in Egyptian children. In addition determination of serum immunoglobulins lgA, IgG, IgE using radial immunodiffusion revealed that there was a significant rise of lgE in the serum of patien ts in contrast to the control group. While serum lgG and IgA showed no significant difference between both groups. So, it was concluded that there is a more or less very marked correlation between pediculosis particulary of the head and cervical lymphadenopathy on one hand and high serum IgE levels on the other hand. |