الفهرس 
AbstractOnly 14 pages are availabe for public view
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Abstract
Stress shielding of the tibial component has remained one major cause of failure after total knee replacement surgery (TKR). A relatively high stiffness of the prosthesis can cause most of the load to be transferred through the prosthesis rather than the bone, which is known as stress shielding. It leads to the resorption of the bone and a decrease in the bone strength and stiffness. Aseptic loosening is caused due to relative motion between the component and the bone caused by stress shielding. It means increasing in the interface shear stress between the cancellous bone and the stem which leads to pain, instability and loss of function. Another problem is stress concentration at tip region of the prosthesis which causes patient’s pain.The present study investigates the optimum design for increasing stress under the upper part of the proximal uncemented tibia tray, cancellous bone, to relieve the stress shielding with decreasing interface shear stress between the cancellous bone and the stem, and decreasing stress at the tip region of the prosthesis to reduce the patient’s pain by changing:The dimensions of the metal tibial tray (shape optimization)The material of tibial tray (material selection).