الفهرس 
AtherosclerosisOnly 14 pages are availabe for public view
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Abstract
T
his study was conducted at the Cardiology Department at Nasr City police Hospital. The study comprised seventy patients who is presented with anginal or atypical chest pain and were being referred from clinic for non emergent multislice computed tomography in the period from December 2014 to December 2015.
A simple method for accurately determining coronary artery diameter would be valuable if differences could be shown between the normal population and patients with early coronary atherosclerosis.
Aim of the study is to shows the feasibility of measuring coronary artery diameters by means of non contrast MDCT and to correlation the increased coronary artery diameter to CAC and to traditional cardiovascular (CV) risk factors using non contrast MDCT.
Full clinical examination was carried out. The resting heart rate and blood pressure were recorded. Chest examination was done to rule out patients with reactive airways. Routine cardiac examination was carried out. The patient’s lab investigations were reviewed especially serum creatinine.
After controlling the heart rate, the patients were transferred to the scanning room where he will lay on the CT couch.
Electrocardiographic triggering was used so that each image was obtained at the same point in diastole, corresponding to 75% of the RR interval. Complete coronary artery views were obtained without contrast-medium injection and at least 35 consecutive images were captured at 2.5-mm intervals beginning 1 cm below the carina and progressing caudally to include the proximal coronary arteries.
Coronary artery diameters were associated with CAC and with the presence of traditional CV risk factors.
Then the results were calculated and statistically analyzed by the SPSS software
The obtained results revealed the following:
LMCA diameter has no significant relation with any risk factors age, sex, smoking, diabetes, hypertension, Obesity, DLP or positive family history of premature coronary artery disease. (P>0.05).
Our finding of larger diameters of the LMCA were more likely to be with high CA score P value =0.012.
RCA diameter has no significant relation with risk age, sex, smoking, hypertension, DLP or positive family history of premature coronary artery disease. (P>0.05).
Meanwhile Study participants with larger RCA diameters were more likely to be diabetics and with higher body mass index (BMI) P value = 0.023 and 0.007 respectively.
The study results of the relation between risk factors and higher local atherosclerotic burden suggests a link between arterial remodeling and the severity of atherosclerosis.
This screening method is potentially useful in detecting early coronary artery atherosclerosis and increasing our understanding of subsequent risks of CV disease.