الفهرس 
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Abstract
Obesity has assumed pandemic proportions mainly attributable to dietary
habits and sedentary lifestyles. More than 1.7 billion adults are overweight and
at least 300 million of them are clinically obese (Deitel, 2003).
It is a major contributor to the global burden of chronic disease and
disability. Often co-existing in the developing countries with under nutrition,
obesity is a complex condition, with serious medical, social, psychological, and
economical implications, affecting virtually all age groups (World Health
Organization, 2000).
The comorbidities include type 2 diabetes, cardiovascular disease,
hypertension, hyperlipidemia, hypoventilation syndrome, asthma, sleep apnea,
stroke, pseudotumorcerebri, arthritis, several types of cancers, urinary
incontinence, gallbladder disease, and depression (Fuks et al., 2001).
Obesity shortens life expectancy with increasing BMIs, resulting in
proportionally shorter lifespan (Moorehead et al., 2003).
With over 300,000 victims in the USA each year, morbid obesity is
projected to overtake smoking as the leading cause of death in the near future
(Braghetto et al., 2007).
Non-operative management with diet, exercise, behavior modifications,
and medications rarely achieves adequate sustainable weight loss. Surgery is the
only proven long-term effective treatment for morbid obesity (Mognol et al.,
2005).
Laparoscopic sleeve gastrectomy (LSG) gained popularity over the last
few years (Strain et al., 2009).
Numerous studies have evaluated the effect of Laparoscopic Sleeve
gastrectomy on fasting lipids, overall showing beneficial changes such as
lowering cholesterol, TGs and LDL-cholesterol and increasing HDL-cholesterol
(Lang R et al.,2012)Thirty five patients with morbid obesity (28 female &7males) ranging in
age between 20-48 years with BMI range (40.05–72.27) ) kg/m2 were included
in the present study.
Most of patients were suffered from one or more of obesity related
diseases such as (T2DM, HTN, chronic joint pain or hyperlipidemia). All
patients had LSG and completed the 2 years follow up period. Those patients
were selected according to the preformed inclusion criteria.
All patients were subjected to pre and post operative assessment after
exclusion of any hormonal imbalance such as hypothyroidism or Cushing
syndrome (complete blood count, liver and kidney function tests , fasting and
postprandial blood sugar , coagulation profile , ECG , echo-cardiograph , chest
X-ray, respiratory functions , abdominal ultrasonography and duplex study of
lower limb venous system ).
LSG proved to be an effective type of bariatric surgery, this is evidenced
in the metabolic and biochemical outcomes following LSG in the form of :
Reduction of body weight regarding (% excess weight loss) , improvement of
obesity related comorbidities.
80% ,80%,75% of diabetic, hypertensive, and hyperlipidemic patients
respectively had improved. in addition to that, all patients of chronic joint pain
showed significant improvement after 2 years of LSG.
This study confirmed the effect of LSG in treatment of morbid obesity
and improving metabolic complications related to it.