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العنوان
Significance of circulating serum Hepatocyte
Growth Factor in the development of carotid
atherosclerosis and ischemic stroke /
المؤلف
Afifi, Khaled Hatem Marouf.
هيئة الاعداد
باحث / خالد حاتم معروف عفيفي
مشرف / وفيق محمود الشيخ
مناقش / أحمد محمد الشريف
مناقش / اكثم اسماعيل الأمام
الموضوع
serum Hepatocyte. ischemic stroke.
تاريخ النشر
2015.
عدد الصفحات
176 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
علم الأعصاب السريري
تاريخ الإجازة
1/12/2015
مكان الإجازة
جامعة المنوفية - كلية الطب - قسم الأعصاب
الفهرس
Only 14 pages are availabe for public view

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Abstract

Ischemic stroke is a wide spread disease affecting large number of
population and causing a great mortality and morbidity with the
accompanying social, psychiological and economic problems.
Carotid atherosclerosis has been associated with increased risk of
stroke and poorer cognitive performance in older adults.
An important cause of stroke is the transformation of a quiescent
carotid artery atherosclerotic lesion into an unstable morphology, which
becomes vulnerable to rupture and thromboembolism.
It is hypothesized that (HGF) may play a role in the natural history of
atherosclerosis and hence the pathogenesis of cardiovascular diseases ,
including ischemic stroke.
we conducted the present study to determine the relation between the
level of circulating (HGF) and carotid vessel atherosclerosis in ischemic
stroke , and if it differs between stroke subtypes ( Atherothrombotic versus
Cardioembolic). Also to answer the question if (HGF) could serve as an
indicator of stroke severity & its role in the prognosis.
This study was conducted on (100) acute ischemic stroke, enrolled from
Neuropsychiatry department, Menoufia University Hospital. The patients
were 2 groups (carotid atherosclerosis & cardioembolic).