الفهرس | Only 14 pages are availabe for public view |
Abstract In recent years, infection with cytomegalovirus (CMV) was the subject of numerous studies for three reasons the first, being the most frequent congenital infection in newborns , the second is the increased incidence of sequelae (about one third of childhood deafness is due to CMV), and the third reason being the most frequent and serious opportunistic infections in immunocompromised individuals. Neonatal CMV infection, is approximately symptomatic in 10% of newborns at birth. Of the remaining 90%, asymptomatic at birth, 10- 15% will develop sequelae later on. Despite detailed knowledge about the epidemiology and pathogenesis of CMV disease in pregnant women, this infection remains largely unknown to most women. This study was carried at Tanta University Hospitals on 2135 patients are classified into 2 major groups : group I the non pregnant cases (820 cases) and group II the pregnant cases (1315 cases) . The 2 groups are further divided into group A includes the negative CMV IgM and/or IgG cases and group B includes the positive CMV IgM and significant IgG cases ( Significant means 4 fold increase in the initial level). |