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العنوان
Chemical study of palm dates (phoenix Dactylifera L) fruits extracts and evaluation of its biological activities
المؤلف
Abd Elrahman, Seham Ahmed Mahmoud
هيئة الاعداد
باحث / سھام احمد محمود عبد الرحمن
مشرف / اماني محمد ضياء الدين المسلمى
مشرف / عبد العزيز محمد حسين
مشرف / اماني محمد ضياء الدين المسلمى
الموضوع
00 000
تاريخ النشر
2015
عدد الصفحات
243P.:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الكيمياء
تاريخ الإجازة
25/2/2016
مكان الإجازة
جامعة الزقازيق - كلية العلوم - الكيمياء
الفهرس
Only 14 pages are availabe for public view

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Abstract

Phoenix dactylifera L is one of the most useful traditional medicinal plants. Previous studies demonstrated that it has many pharmacological actions such as antibacterial, anti-inflammatory, anti-diabetic, anti-asthamatic, nephroprotective and hepatoprotective activities. Moreover, previous studies demonstrated that its fruits and seeds contain many chemical substances such as anthocyanins, phenolics, sterols, carotenoids and flavonoids. So, the present study was designed to analyze its phenolics and flavonoids contents using HPLC – PDA as well as to to investigate the effect of aqueous and methanolic extracts of fruits and seeds of palm dates on diabetic nephropathy in type 2 diabetic rats.. The results of this study revealed that the extracts of palm dates contain phenolic compounds e.g. caffeic, gallic, ferulic, p-coumaric, sinapic, chlorogenic acid and falvonoid compounds e.g. apeginin, quercitin and luteolin glycosides in fruit and vanillic acid, gallic acid, caffeic acid, p-Coumaric acid and quercitin in seed. Also, both fruit and seed extracts caused significant improvement in glycaemic control and kidney functions in diabetic rats. We concluded that both fruit and seed extracts have renoprotective in type 2 diabetic rats which might be due to their phenolics and flavonoids contents.