الفهرس | Only 14 pages are availabe for public view |
Abstract Candida is a genus of yeasts and is the most common cause of fungal infections worldwide. Many species are harmless commensals of hosts including humans; however, when mucosal barriers are disrupted or the immune system is compromised they can invade and cause disease.[22l] Candida albicans is the most commonly isolated species, and can cause infections in humans. However, the importance of some non-albicans species, particularly Cparapsilosis, C tropicalis, C. glabrata or C. Krusei has recently increased. The problem has been magnified by reduced susceptibility of Candida species to some of the currently available antifungals. Antifungal drug resistance is a confounding factor that negatively impacts clinical outcome for patients with mycosis. Early detection of fungi in blood or other specimens with a rapid assessment of drug susceptibility is necessary to initiate appropriate antifungal treatment. This study was designed to assess the occurrence of Vulvovaginal Candidiasis among pregnant women in different trimesters and identification of isolated species, in addition to test susceptibility pattern of Candida isolates to antifungal agents including Fluconazole and Nystatin. In order to achieve these objectives, four groups according to pregnancy trimesters were included i~ this study: Group 1: Patients in the first trimester complaining from Itching or/and vaginal discharge. Group 2: Patients in the second trimester complaining from Itching or/and vaginal discharge. |