الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 188 |  |  |
| | | from | 188 | | |
Abstract
The importance of studying Ps.aeruginosa microbes was attributed to
the opportunistic nature of this bacterium, it also represent one of the most
dangerous bacteria that causes nosocomial infection, as well as the high
capability of this microorganism to acquire resistance against the different
classes of antimicrobial chemotherapeutics and disinfectants.
The current study aimed to find the correlation between reduced
susceptibility to disinfectants and multidrug resistance among clinical
isolates of Pseudomonas aeruginosa.
Two hundred and forty specimens were collected from patients with
various clinical cases including burn, wound, UTI, blood, otitis media, and
respiratory tract infection samples from the Mansoura University Hospitals.
The specimens were processed and yielded 104 non duplicate isolates
that were identified as Ps.aeruginosa based mainly on their growth on
cetrimide agar, oxidase test, motility test, pyocyanin pigment production and
growth at 42 ᵒC.
The susceptibility of Ps.aeruginosa isolates to different members of
antipseudomonal drugs were determined by agar disk diffusion method.
The isolates showed high sensitivity to piperacillin (79.8%),
imipenem (78.84%), amikacin (73%) and gentamicin (69.23%). Meanwhile
these isolates showed high resistance to sulfamethoxazole/trimethoprim
(56.73%) and carbenicillin (100%).
Out of 104 isolates, 36 were classified as MDR, being resistant to 3
groups or more of antimicrobial chemotherapeutic agents.