الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Children with cancer diseases are at risk of sever infections especially who have not completed their primary immunizations.Vaccination of these children presents challenges due to efficacy and safety concerns. There is a little of data on several species of vaccination in this group of children.
Immunization works because of the intact immune system’s complex network of lymphocytes and effector cells generate memory and specificity .Immune dysfunction due to disease or the treatment of the disease affects different elements of the immune system to varying degrees, and this in turn determines the effectiveness and safety of specific vaccines. Some immunocompromised children and adolescents at particular risk of certain infections will benefit from extra immunization.
Chemotherapy suppresses immune response, which is most marked during induction and consolidation phase, and is moderate during maintenance phase. After the cessation of all therapy, immune function recovers to normal within three months or more.
Children with cancer are more susceptible for Hepatitis infection as a result of recurrent blood transfusion and also due to suppressed immune system. The national immunization Program plays an important role in deceasing subsequent hepatitis B infection in children with cancer