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العنوان
Using of local steroids in treatment of nasal obstruction caused by adenoid hypertrophy in children /
المؤلف
Zaher, Peter Sobhy.
هيئة الاعداد
باحث / بيتر صبحي زاھر
مشرف / محمد عبد القادر احمد
mohamed_ahmed14@med.sohag.edu.eg
مشرف / وائل عبد المنعم احمد
wael_ahmed@med.sohag.edu.eg
مناقش / عبدالمتين موسي
مناقش / محمود محمد راغب الشريف
الموضوع
Steroids. Adenoid Diseases. Nose Diseases diagnosis. Pediatric otolaryngology. Otorhinolaryngologic Diseases therapy.
تاريخ النشر
2014.
عدد الصفحات
63 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الحنجرة
تاريخ الإجازة
9/9/2014
مكان الإجازة
جامعة سوهاج - كلية الطب - الأنف والأذن والحنجرة
الفهرس
Only 14 pages are availabe for public view

from 64

from 64

Abstract

Summary&Conclusion
Background:
Adenoid hypertrophy is associated with high morbidity rate in children. Although surgical treatment is indicated in severe cases, however, there are evidences that some medical interventions are effective in improvement. This study was done to evaluate the effectiveness of beclomethasone nasal spray on reduction of airway obstruction due to adenoid hypertrophy.
Methods:
In a clinical trial study 30 children between the ages of 4-10 years suffering from obstructive symptoms caused by adenoid hypertrophy were divided into two groups, first group were administered beclomethasone nasal spray (2 puffs each 12 hr) for duration of 24 weeks and the second group administered normal saline as the same way as the first group . All subjects were evaluated for adenoid size and grade of airway obstruction before and after the intervention by fiber-optic nasopharyngoscopy. A symptoms scale was filled in by subjects’ parents to assess obstructive symptoms before and after the intervention.
Results:
endoscopic findings revealed that after treatment adenoid size was significantly less than its size before treatment and airway diameter was significantly more than before treatment. Also finding showed that severe and moderate forms of nasal obstructive findings after intervention were significantly less frequent than before it.
Conclusion:
There appears to be a pathophysiologic association between AH and allergy, suggesting a role for INS in the management of patients with AH. ,Our study demonstrate the efficacy of INS in reducing obstructive nasal symptoms and the size of adenoid pads in children with AH.,Proposed mechanisms for the INS activity in AH include direct lympholytic action, inhibition of inflammation, and alteration of adenoidal bacterial flora. INS may offer a new non-surgical treatment option for some children with AH and have been shown to reduce the need for adenoidectomy for children .