الفهرس 
Introduction and aim of the workOnly 14 pages are availabe for public view
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Abstract
Preoperative assessment of renal anatomy is crucial during donor work-up as well as before other renal operations. Supernumerary arteries and early branching anomalies are of particular importance. Also, preoperative imaging should give sufficient information on variants of renal veins and ureters. Now, MDCT angiography has replaced DSA as the method of choice for assessing renal vascular anatomy and variants. Also it has superior sensitivity for detection of small accessory renal arteries compared to MRI.
Assessment of renal function is very important in renal transplantation for both donors and recipient. The better kidney should be preserved for donors. Assessment of renal function is usually done by isotopic renographic studies using different pharmaceuticals to measures split renal function and single kidney GFR. The study included 51 kidney donors, they were examined by our MDCT protocol and their anatomical findings were evaluated as regarding presence of arterial or venous anomalies and any associated pelvi-calyceal system abnormalities. In addition to anatomical evaluation, functional evaluation was done by estimation of perfusion parameters on each side. We used two methods of processing while drawing region of interest (ROI) in the kidney. In method 1: ROI was drawn around the renal cortex only, while in method 2 ROI was drawn around the whole kidney parenchyma including cortex and medulla. We compared the results of perfusion CT obtained by the two methods with each other. We calculated split values of each of these parameters and compared them with the split renal function obtained by MAG3 renography. Our results showed feasibility of certain parameters to estimate split renal function with results comparable to those of isotopic study.
64-section MDCT can provide accurate morphological information, regarding the anatomy of the urinary tract and renal vasculature. It can detect renal and vascular abnormalities that might be potentially significant for safe renal donation. In addition, perfusion CT can be used as alternative method for renal function assessment including estimation of split renal function. This will allow both anatomical and functional evaluation of kidney donors in one session examination.