الفهرس 
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Abstract
This study aimed to : The relationship between Helicobacter pylori (H. pylori) infection and chronic idiopathic thrombocytopenic purpura (ITP) has been confirmed; however, no clear evidence for the effectiveness of H. pylori eradication on ITP exists thus far. The purpose of this study was to investigate platelet recovery in chronic ITP after H. pylori eradication. Methods A total of 40 patients (30 male, 10 female; the median age of 37.75±12.778 years) diagnosed with ITP, whose platelet counts were less than 100×109/L, were enrolled. They were tested for H. pylori infection by the stool antigen test (SAT). All patients received triple therapy for 7 or 14 days to eradicate H. pylori infection combined with standard ITP therapy. Results Of the 40 patients, 27 (67.5%) were diagnosed with H. pylori infection. Of all the ITP patients, 17 (63%) exhibited a complete response (CR) to H. pylori eradication therapy; 7 (25.9%) a partial response (PR); and 3 (11.1%) were nonresponsive (NR).Conclusion In the present study, the effect of eradication (alone) therapy and eradication (combined) with immunosuppressive therapy was not compared, as all the H. pylori-positive patients received eradication therapy combined with immunotherapy. Although the H. pylori positive group treated with combined eradication and immunosuppressive therapy did not show a superior response rate, the group achieved apparently longer response duration. Therefore, in our opinion, there is insufficient evidence to include only eradication for ITP patients having an H. pylori infection.