الفهرس 
Sickle Cell AnemiaOnly 14 pages are availabe for public view
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Abstract
SNHL is a well recognized complication of sickle cell disease, Labyrinthine hemorrhage (LH) and labyrinthitis ossificans (LO) have been reported to affect the inner ear in sickle cell disease; however, the association between inner ear involvement and imaging findings has not been fully described.
Our purpose was to examine the prevalence of inner ear involvement in patients with sickle cell anemia by magnetic resonance imaging and to assess the relationship between auditory function and imaging findings in such patients.
All patients were subjected to history taking and revision of hospital records for details of diagnosis including age,
hemoglobin electrophoresis, ransfusion, chelation, hydroxyurea, hospital admission and sickle cell disease complication followed by audiogram, MRI inner ear and transcranial doppler.
Abnormal MRI of inner ear in the form of hyperintensity of vestibule and semicircular canal, cochlear neuropathy and adenotonsillar hypertrophy was found in ( ) patients; there was no difference between patients with normal and abnormal MRI regarding age, age at diagnosis, transfusion, chelation, hydroxyurea use or other sickle cell disease related complications.
Left MCA was higher in patients with abnormal MRI ( cm/sec) compared to patients with normal MRI ( cm/sec); however there was no difference inTCD flow velocity of basilar artery, vertebral artery or posterior cerebral artery. There was no difference in mean hearing level between both groups.
SNHL was present in ( ) and CHL in
( )patients, patients with SNHL had higher age ( years) compared to patients with normal hearing ( years) and patients with CHL ( years) P= ,weight for age SDS was higher in patients with CHL( ) and height for age SDS ( ) were higher in patients with
CHL compared to patients with SNHL ( , - . )
and patients with normal hearing(- ,- ) P= , respectively.
There is also significant negative correlation between mean hearing level on the right ear and right middle cerebral artery flow velocity and also significant negative correlation between mean hearing level on the left ear and basilar artery flow velocity.