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العنوان
An epidemiological study of hepatitis b virus and hepatitis c virus in matrouh /
المؤلف
Ghorab, Mohamed Abd-EL Hakeem.
هيئة الاعداد
باحث / محمد مجدى الصادق عطا
مشرف / محمود فوزى الجندى
مشرف / انتصار حسين الشرقاوى
مشرف / عباده محمد سعيد
الموضوع
Hepatology, gastroenterology and infectious diseases.
تاريخ النشر
2014.
عدد الصفحات
76 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الجهاز الهضمي
تاريخ الإجازة
1/1/2014
مكان الإجازة
جامعة بنها - كلية طب بشري - الجهاز الهضمى والكبد
الفهرس
Only 14 pages are availabe for public view

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Abstract

Summary
Marsa matrouh is an impotent area on Mediterranean Sea in Egypt. It’s about 240 kilometers west of Alexandria, 485.376 thousands people live in it .They have special habits like khizam and tattooing.
HBV is a virus responsible for acute and chronic liver diseases .blood transfusion is main cause of infection.
HCV is the virus responsible for severe liver disease and studies showed that about170 million people are infected with this virus worldwide.
Infection with HBV&HCV are main cause of liver disease worldwide and the patient may not having symptoms and may be only a carrier for years .Chronic infection with these viruses may lead to liver cirrhosis, liver cell failure and cancer liver. Some studied the prevalence of HBV&HCV in Marsa Matrouh, mode of transmission and the role of special habits of Marsa Matrouh people in this infection, this study was done on patients attending Marsa Matrouh general hospital from October 2011 to December 2012 to identify the following:
1- The prevalence of HBV&HCV infection in Matrouh.
2- The sociomedical aspects of patients suffering from any or both diseases.
3- The modes of transmission &risk factors of both diseases in this important area in Egypt.
The patients were investigated as regard the following:
1- Full history taking with stress on risk factors for viral transmission, using a well prepared questionnaire to collect their data.
2- Clinical examination with stress on organomegaly, ascites and other manifestations of liver cell failure.
3- Laboratory investigations (blood picture –liver function tests –serum creatinine- HCV antibodies – HBV surface antigen – HBV core-IgG-IgM).
4-Abdominal Ultrasonography.
A written informed consent was taken from each patient, before participating in this study.
36(7.1%) of 504 were HCV positive while 24(4.8%)were HBV positive.
Regarding HCV infection 12 subjects exposed to blood transfusion 3(8.3%) were positive ,63 exposed to khizam 7(19.4%) were positive and 41 exposed to tattooing 3(8.3%) were positive .
HB%,platelets count and WBCs were significantly higher in HCV negative group than that in the HCV positive group,while SGPT,SGOT,total,direct billirubin and s.creatinine were significantly higher in HCV positive group than in the negative one.
Regarding HBV infection 12 subjects exposed to blood transfusion,63 exposed to khizam and 41 exposed to tattooing ,this resulted in 2(8.3%),2(8.3%) and 2(8.3%) were positive respectively.
Platelets count was higher in HBV negative group in comparison to HBV positive ,however there were no significant differences between both groups as regards HB%,WBCs and creatinine.
Serum albumin level was significantly lower in HBV positive group than HBV negative group, however there were no significant difference between both groups as regards the other parameters of liver functions .