الفهرس | Only 14 pages are availabe for public view |
Abstract This study aimed to : Introduction: Brachial plexus root avulsion which can occur in both traumatic and obstetrical brachial plexus injuries remains a challenging problem to surgeons all over the world. So searching for a new method for repair supported by stem cells transplantation may be helpful for these patients. Materials & Methods: This study was conducted in Mansora Research Center (MRC), Mansoura Faculty of Medicine. This study was carried out on 30 adult spraque Dawely rats divided into three groups; first group will be offered surgical reimplantation using micro-sutures, second group will be subjected for surgical reimplantation using fibrin glue and third group will be offered surgical reimplantation using fibrin glue combined with transplantations of highly purified neural stem cells. Results: There is no significant difference in the clinical improvement in the three groups but pathological examination showed much more improvement in the third group which shows more rapid improvement in rats. Also, fibrin glue has the same effect as microsurgical sutures. Conclusion: Reimplantation of avulsed roots of brachial plexus is a good method of brachial plexus repair specially if assisted by stem cells transplantation. |