الفهرس 
staphulococcus.aureusOnly 14 pages are availabe for public view
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Abstract
Thermal injury is one of the most common traumas in daily life, and the causes are in great diversity. In China millions of burns happened every year, while in the USA 1.2 million burns occurred because of fires every year.
S. aureus is a major human pathogen causing a great number of illnesses, ranging from skin & soft tissue infections and toxin-mediated disease to invasive infections. The emergence and spread of MRSA among burn centers results in number of poor outcomes such as prolonged hospitalization, economic burden, bacteremia or sepsis and even death, which prompts great urgency in the development of and advocacy for prevention and treatment efforts.
The present study was conducted to: Detect prevelance of staphylococcal infection in patients admitted to burn unit at Fayoum hospital.Typing of staphylococci isolates by antibiogram and Determine prevelance of infection by different types of staphylococci strains isolated from wound specimen collected in the burn unit.
Burn sites of 400 patients were swabbed and cultered on conventional culture media. Isolates were identified using conventional biochemical tests. S.aureus and MRSA isolates were identified using conventional methods and culture on chromogenic agar (ORSAB) and were confirmed by molecular method real-time polymerase chain reaction (RT-PCR).
The present study detected s.aureus in (40%), MRSA in (26%) and CONS in (8%) of studied cases and no VRSA or VISA were detected. Out of 400 cases ORSAB media detect 96 cases of MRSA while RT-PCR detect only 80 cases. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) of RT-PCR were 83.3%, 100%, 100% and 80% respectively.
Risk factors for acquisition of staphylococcal burn wound infections in the present study include: male sex, old age (50-60 years old), large burn surface area (BTBSA ›70%), burns in head and neck, and intake of cefaxone antibiotics.
Careful surveillance of infection, good isolation techniques, procedure routines and a restrictive antimicrobial policy can keep antimicrobial resistance rates as well as infection rates low in infection-prone burn patients.