الفهرس 
AbstractOnly 14 pages are availabe for public view
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Abstract
Misoprostol is inexpensive, easily stored and widely available, which likely means that it would be more accessible, particularly for women in some parts of the developing world, than other proven medical abortion regimens. Because research on misoprostol has been driven by individual researcher interest and not drug development efforts by a pharmaceutical company, studies on misoprostol for early abortion do not necessarily follow a clear pattern, and data are often not comparable. So, the present study aims to compare the effectiveness of a multiple vaginal doses with a multiple oral course of misoprostol in the management of early pregnancy failure. To accomplish this target, the study involved 80 women were randomly assigned one of two groups using the sealed envelope technique. Each group received one of the following treatment protocols: Group I (Vaginal group): included 40 patients who received 400 µg misoprostol every 8 hours for 3 days vaginally. Group II (Oral group): included 40 patients who received 200µg misoprostol every 8h for a maximum of 7 days Comparison between the success rate of vaginal and oral routes in the present study found a significantly higher frequency of success was significantly higher in the vaginal group. In the present study, comparison between successful and failed cases in the vaginal group regarding the demographic characteristics had shown no significant differences regarding BMI. In the current study, comparison between the study groups regarding the reported pain had shown no significant differences. Also, our study showed no significant differences between the studied groups regarding the reported bleeding. Comparison between the studied groups regarding the other side effects had shown no significant differences between the studied groups. Comparison between the demographic and obstetric characteristics in successful and failed cases in oral and vaginal groups didn’t show significant differences.