الفهرس 
Anatomical and Histological aspects of the human corneaOnly 14 pages are availabe for public view
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Abstract
Diabetes mellitus (DM), a life long progressive disease, is the result of the body’s inability to produce or use insulin to its full potential. It is now considered to be an epidemic disease. Subsequently, with marked increase in its prevalence there is parallel increase in its serious complications. One of the most important diabetic complications is that affects the eye as it frequently leads to complete loss of vision. Recently, diabetic keratopathy (DK) and retinopathy (DR) had attracted major power of both clinical and basic researches because of their clinical importance. Therefore, to prevent the diabetic ocular complications, prophylactic medical treatments are needed other than glycemic control. So this study was done to elucidate the damaging effects of both DK and DR and to explore the possible protective role of ginger Seventy five adult male albino rats weighing from 180-200 grams were used in this study. They were classified as follows Group I: Included forty five adult male albino rats and were further subdivided into three equal subgroups:
Subgroup Ia (plain control): Consisted of fifteen adult male albino rats fed on standard diet, each of them was kept without any treatment all over the experimental periods.
Subgroup Ib (vehicle control): Consisted of fifteen adult male albino rats.
They were fed on standard diet and each rat received a single intraperitoneal injection of 0.2 ml distilled water “solvent of streptozotocin (STZ)”.
Subgroup Ic (ginger treated group): Consisted of fifteen adult male albino rats. Each rat received ginger extract once daily orally by intragastric tube at a dissolved in 2 ml distilled water.
Five rats from each subgroup were anaesthetized and then sacrificed at the same timing schedule corresponding to that of the diabetic and ginger treated diabetic groups.
Group II (diabetic group) (STZ treated group): Consisted of fifteen adult male albino rats. Diabetes was induced by a single dose (50 mg/ kg) of STZ by intraperitoneal injection. After diabetes confirmation test, the rats were further subdivided into three equal subgroups (IIa, IIb and IIc), five rats each, that were sacrificed at the end of the 4th, 6th and 8th week after induction of diabetes.
Group III (ginger treated diabetic group): Consisted of fifteen adult male albino rats. Diabetes was induced. After diabetes confirmation test, they received ginger extract once daily at a dose (500 mg/kg/day) orally by intragastric tube. The
rats were further subdivided into three equal subgroups (IIIa, IIIb and IIIc), five rats each, they were sacrificed at the end of the 4th, 6th and 8th week after induction of diabetes.
At the end of the experiment and according to the previously mentioned timing schedule, the rats were weighed and blood samples were obtained from retro-orbital venous plexus for biochemical study (blood glucose and glycated haemoglobin levels The rats were anaesthetized lightly by diethyl ether inhalation and sacrificed by cervical dislocation.