الفهرس 
LeukemiaOnly 14 pages are availabe for public view
 |  | from | 175 |  |  |
| | | from | 175 | | |
Abstract
Acute lymphoblastic leukaemia, accounts for about 75 % of the childhood leukemias. The proliferation and accumulation of blast cells in the marrow, results in suppression of hematopoiesis and thereafter anemia, thrombocytoprnia and neutropenia. Extramedullary accumulations of lymphoblasts may occur in various sites. Adding methotrexate (MTX) to leukemia treatment protocols has been associated with an increased survival rate in children with acute lymphoblastic leukemia. The efficacy of this agent is often limited by its toxicity which causes severe side-effects. The toxic effect of anticancer drugs may be reduced if supplemented with natural anti- oxidants plant products.