الفهرس 
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Abstract
This study included 40 patients who underwent rectal anastomosis, GI anastomosis, small bowel anastomosis in the obstructed one or.
After completion of the anastomosis, the patients were randomized into two groups. In group I (n = 20), the anastomotic site was covered with 2 ml of fibrin glue (Tisseel VH; Baxter, Deerfield, IL, USA), and in group II; the control group (n = 20), the fibrin glue was not used. Fibrin sealant, Tisseel™ (Baxter, Glendale, CA), was applied intraoperatively with a double syringe dispensing unit provided in the kit.
The primary postoperative outcome measures included occurrence of anastomotic leak in 2 weeks. The secondary outcome measures included the evidence of infectious collections in the anastomotic area in 3 months after surgery.
There was insignificant difference in age, sex difference, frequency of preoperative co-morbidities, priority of operation, preoperative laboratory data, preoperative bowel preparation, indications of bowel resection-anastomosis, and site of anastomosis in both groups.
The mean of total operative time was 146 ± 41 minutes in fibrin glue group and 135.6 ± 42 minutes in control group, with insignificant difference between both groups.
The mean time for first bowel movement was 4±1.2 days in fibrin glue group and 4.4±1 days in control group, with insignificant difference between both groups.
The mean of hospital stay was 10.8 ± 3.6 days in fibrin glue group and 11.3±4.1 days in control group, with insignificant difference between both groups.
There was insignificant difference in frequency of postoperative complications between both groups, except a significant decrease in frequency of anastomotic leak in fibrin group. There were no cases with anastomotic leak in fibrin glue group, while it occurred in 4 patients (20%) in control group.