الفهرس 
AnemiaOnly 14 pages are availabe for public view
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Abstract
Summary
I
ron deficiency anemia is the most frequent form of anemia in pregnant women. The diagnosis of IDA relies on blood hemoglobin and plasma ferritin.
The prevalence of prepartum anemia in the third trimester ranges 14-52% in women taking placebo and 0-25% in women taking iron supplements. The frequency of IDA in placebo-treated women ranges 12-17% and in iron-supplemented women 0-3%.
Dietary measures are inadequate to reduce the frequency of prepartum IDA, which, is prevented by oral iron supplements 30-40mg ferrous iron per day taken at bedtime or between meals from early pregnancy to delivery.
Treatment of IDA should aim at replenishing body iron deficits by oral and/or intravenous administration of iron.
Treatment with intravenous iron is superior to oral iron concerning the hematological response and is considered safe in the second and third trimester.
Intravenous iron should be considered if oral iron fails to increase hemoglobin within 2 weeks, at profound IDA with hemoglobin of <90g/L in any trimester beyond 14 weeks gestation and at IDA in the third trimester.
Severe IDA requires prompt intervention, especially in women who for various reasons oppose blood transfusions.
Several intravenous iron preparations are available with different profile of safety and efficacy.
According to information of the researcher, no previous studies evaluate intravenous administration of iron polymaltose complex (IPC) in treatment of severe anemia with pregnancy. Thus, this study was designed to explore this point. Fifty pregnant females were included and evaluated clinically and by laboratory parameters.
The results of the present study prove that IPC showed highly effectiveness in the treatment of iron deficiency anemia in pregnant women. It has nearly no side effects and thus, it can be considered as a useful, relatively novel, and alternative formulation for the treatment of IDA during pregnancy. However, further studies with large patient populations are required to strengthen the evidence of the present study.