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العنوان
Urinary Tract Infection as a cause of br Neonatal Hyperbilirubinemia /
المؤلف
Abdel Wahab, Ahmed Mohammed Ibrahim.
هيئة الاعداد
باحث / احمد محمد ابراهيم عبد الوهاب
مشرف / محسن حسن حسين
مناقش / هناء احمد العربي
مناقش / محسن مليجي ديب
الموضوع
Pediatrics.
تاريخ النشر
2013.
عدد الصفحات
98 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/2013
مكان الإجازة
جامعة المنوفية - كلية الطب - طب الاطفال
الفهرس
Only 14 pages are availabe for public view

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Abstract

Neonatal jaundice is one of the most common reasons for br admission in neonates and young infants . Physiological jaundice occurs br in first week of life in 60% of term and 80% of premature neonates. Non br physiologic or pathologic jaundice occurs due to underlying disease. The br causes of neonatal jaundice are numerous ,and may include infections, br hemolytic ,metabolic and endocrine dis-#111;-#114;-#100;-#101;-#114;s. br Urinary tract infection is seen in 5 to 11% of febrile neonates under br 8 weeks of age . Previous studies have found that jaundice may be one of br the initial symptoms related to urinary tract infection (UTI) in neonates. br The Clinical manifestations of urinary tract infection (UTI) in br neonates are highly variable, ranging -#102;-#114;-#111;-#109; asymptomatic to severe br systemic infection. Fever or temperature instability, decreased br activity, poor feeding, and jaundice are common nonspecific br findings among infected neonates. Neonates often have failure to br thrive, feeding problems, and vomiting, beside the fever. br This study was done on 105 newborns with neonatal jaundice that br admitted in the NICU in Al-Ahrar hospital , Zagazig City, Sharqia br Governorate. Period -#102;-#114;-#111;-#109; January to August 2012. Newborns who were br excluded were jaundiced patients more than four weeks of age. br - 90 - br Summary br A total of 105 jaundiced neonates were enrolled. Among them, 6 br cases (5.7%) were grouped into the UTI group, and 99 neonates (94.3%) br were grouped into the non-UTI group. br The majority of the studied cases (84 neonates) were in the age br group -lt;8 days , and 65 neonates of them were males . All male neonates br were uncircumcised. 83 % of the studied cases (87 neonates) were br delivered by Cesarean section (CS). Most of the studied neonates had no br past history of maternal infections. br The mean body weight was 3.0 ± 0.39 kg and 2.88 ± 0.64 kg in the br patients with and without UTI, respectively. The mean gestational age on br admission was 38.6 ± 0.7 weeks and 38.5 ± 0.8 weeks, respectively. The br mean serum level of total bilirubin was 16.78 ± 2.29 mg/dL and 12.6 ± br 3.26 in the patients with and without UTI, respectively. The most br common blood group in all neonates and their mothers were A ( 32 % ) , br A ( 30% ) respectively . br This study showed that most of neonates with UTI ( 4 out of 6) br 67% were males and 2 (33%) were females. The mean gestational age for br UTI-group at admission was 38.6 ± 0.7. The mean body weight was 3.0 ± br 0.39 kg. Regarding the isolated microorganisms, E.coli was the most br common organism cultured in 4 cases out of 6 (67%), and the second br most common organism was Klebsiella species. br Our study showed that there was no statistically significant br difference between positive and negative UTI groups as regards br gestational age , weight on admission , mode of delivery , maternal blood br - 91 - br Summary br groups, neonatal blood groups or history of maternal infections (maternal br UTI and PROM ) . br Therefore, performing urinary tests to exclude the possibility of br coincidental UTI may be necessary for admitted jaundiced neonates br younger than 4 weeks old. br -#102;-#114;-#111;-#109; this study we can conclude that : br The incidence of UTI in the admitted neonates with br hyperbilirubinemia was approximately 5.7%. The most common cultured br bacterium in urine was E coli. Therefore, performing urinary tests to br exclude the possibility of coincidental UTI may be necessary for admitted br jaundiced neonates .