الفهرس | Only 14 pages are availabe for public view |
Abstract The Gastric cancer rate differs in the Middle East from very high in Iran (26.1/10 5) to low in Israel (12.5/10 5) and very low in Egypt (3.4/10 5). Epidemiological studies showed that the prevalence of H. pylori is almost similar in those countries with a high level of infection in childhood. In The United States, the American Cancer Society estimates that in 2007, there were an estimated one million new cases , nearly 70% of them in developing countries and about 800,000 death . During the period from 2005 – 2010 the cases of the gastric adenocarcinoma presented to NEMROCK were 81, but only 44 cases received treatment and assessed . The different therapeutic majors were compared whether surgery , chemotherapy alone , radiotherapy alone or combined modality. It was found that using surgery had the highest median survival reaching 43 months. In absence of surgical intervention , using chemotherapy only or chemoand radiotherapy had no effect on median survival. Comparing the different regimens applied, ( ECF, FOLFOX, CIS/5FU, Lev/5FU), they were comparable in terms of median survival , but time to disease progression was significantly higher in patients who received Leucoverin /5 Fu and lower in those who received Cisplain / 5Fu. Key word: T.T.P: Time To Disease Progression. |