الفهرس | Only 14 pages are availabe for public view |
Abstract This study aimed to evaluate the relationship between pericardial fat volume and coronary atherosclerosis or coronary plaque burden. The study was conducted on 100 patients who underwent all of the following: A- Assessment of risk factors for atherosclerosis including (Age, sex, family history, diabetes mellitus, hypertension, smoking, Dyslipidemia, BMI and waist circumference). B- Multi-slices CT coronary angiography to measure the following: 1- Measurement of coronary plaque burden using the 16-segment score or segment involvement score. 2- Measurement of pericardial fat volume. C- Conventional coronary angiography to assess the MSCT results. Results of this study showed the following: 1- Increased pericardial fat volume was significantly associated with increased coronary atherosclerosis and significant coronary plaques. 2- PFV increased step-wise with increased coronary atherosclerosis and increased steeply with the presence of significant coronary artery stenosis. 3- Waist circumference (in males only) was significantly associated with PFV, where as BMI was not. 4- LDL.C, HDL.C, total cholesterol and triglycerides were significantly associated with PFV. 5- Other atherosclerosis risk factors including age, sex, DM, hypertension, family history and smoking were not significantly associated with PFV. Thus we conclude that pericardial fat accumulation is significantly associated with coronary atherosclerosis and plaque formation as well as the presence of significant coronary lesion assessed by MSCT. |