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العنوان
Gastrointestinal eosinophils in health, disease and functional disorders /
المؤلف
Shabana, Ahmed Shekeib Abdein.
هيئة الاعداد
باحث / Ahmed Shekeib Abdein Shabana
مشرف / Hasan Mohammed El-Askalany Mohammed
مشرف / Ehab El-Sayed Ibrahim Abd El-Khalek
مشرف / Nader Aly Yousef El-Malky
الموضوع
Eosinophils-- physiology.
تاريخ النشر
2012.
عدد الصفحات
231 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب
تاريخ الإجازة
1/1/2012
مكان الإجازة
جامعة المنصورة - كلية الطب - General Medicine
الفهرس
Only 14 pages are availabe for public view

from 274

from 274

Abstract

Eosinophils are tissue-dwelling and inflammatory leukocytes. They participate in host defense particularly in immunity to helminthes. The only non-hematopoietic organ to contain eosinophils under normal conditions is the gastrointestinal tract, and their distribution is not homogeneous throughout the digestive tract. Resident gastrointestinal eosinophils evoke neither inflammatory reactions nor tissue damage, but under inflammatory conditions, they induce irreversible tissue damage.
Eosinophilic gastroinorderstestinal diseases are rare disorders characterized by the association with increased gastrointestinal eosinophilic infiltrates without any underlying primary etiology. Eosinophilic mucosal infiltration produces nonspecific symptoms which depend upon the organ(s) involved. The entire gastrointestinal tract from esophagus to colon, including bile ducts, can be affected, with the cecal and appendiceal region having the highest concentrations.