الفهرس | Only 14 pages are availabe for public view |
Abstract Alkyl groups attached to aromatic heterocycles behaves very different than alkyl aromatic hydrocarbons. Thus whereas the latter functions are normally inert toward electrophilic reaggents , alkyl aromatic heterocycles, are known to react with a variety of electrophiles under relatively mild conditions.This extra reactivity is attributed to the stabilizing effect of heteroat-olU exerts on the carbanions of alkybeteroarmatic.Howwever, even when alkyl group is linked to a pi-deficient heterrocycle in a posit ion that do not permit this delocalization to occure , extra t:;tability of tbese carbanions is observed. The pi-dificiency of the ring is sufficient to promote and stabilli ze carbanions. In addi t ion to this several subst i tuted al kyllheteroawatics have been reported to react readily with nucleoophilic reagents or at least to exhibit peculiar reactivity tooward these latter reagents. Alkylhelel’o’-ll’Olllatics are readily obtainable either from naaturally occuring sources or via ring syntheses and this wakes \ IH’III \lsl’Jull synl het ic 10015. Al though enormous nUUlber 01 usee111 1 COUI}.lOUl His has 1)(’<”1l pl’epal~ed uti 1 is i ng a 1 ky 1 het reoarOWd tic |