الفهرس | Only 14 pages are availabe for public view |
Abstract This studyexaminesthe impact of garlic powder on atherosclerosis in rabbits from the data derived from multiple scientific studies that used by many of the compounds of garlic and its products, which came with different results. It emphasizes the need to develop standard specifications for garlic products available, to allow better comparison between the results of study, to draw conclusions about the beneficial effects of garlic on atherosclerosis. Forty white male New-Zealand rabbits were used in the experimental investigation of this study. Their weight from 1 to 1.1 kg.The animals were divided into four equal groups, each group containing ten rabbits. The first group is the control group was fed the diet without additives and the second group were fed the diet with added 2% garlic powder, the third group were fed 1% cholesterol supplemented rich diet while the fourth group received cholesterol 1% and garlic 2% rich diet together. After the end of the experiment (one month). The samples were collected from blood and tissues (liver, heart and aorta) from all animals for estimation of: serum total lipid, serum total cholesterol, serum triacylglycerols, serum high density lipoprotein-cholesterol, serum low density lipoprotein-cholesterol, serum very low density lipoprotein-cholesterol, MDA in serum and tissue (liver, heart and aorta) and also serum total free fatty acids. The results showedthat, the additionof garlic powder has asignificant decreasein the level oftotal lipids, total cholesterol, LDL-c and VLDL-cas well assaturated free fatty acidsandMDA in serum on the other hand,differedsignificantlyincreasehigh-density lipoproteinsandunsaturated free fatty acids, two factors ofsafetyto reduce thechances ofhardeningarteries. Recently due to increase stress and fast meals which contain excessive amount of lipids especially cholesterol the addition of garlic decrease the incidence of atherosclerosis and cardiac diseases. On conclusion we adviseincrease feeding of garlic to reduce thedamageresulting fromfree radical andalsoto reduceatherosclerosisand heart disease. |