الفهرس 
The immunobiology of schistosomiasisOnly 14 pages are availabe for public view
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Abstract
Schistosomiasis is one of the most serious diseases suffered by man in Egypt. The pharaohs knew it over 5,000 years ago. The World Health Organization estimates that over 200 million people are infected with schistosomiasis and 400 more are at risk in at least 76 countries.
Vaccine research has focused on the identification and testing of specific schistosome antigens. Over the past twenty years, the laboratory of Dr. Amr Karim at Ain Shams University has identified and cloned a large number of candidate vaccine antigens including most of the major candidate antigens that had been identified previously and many new ones. With the identification of the major antigens likely to be involved in developing a vaccine, the focus now shifts to antigen stability; the production of those antigens in such a way that they are folded and modified properly to preserve native epitopes. Equally important is the manner in which those antigens will be presented to the immune system so that they trigger the appropriate protective responses.