الفهرس 
Introduction and aim of workOnly 14 pages are availabe for public view
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Abstract
The liver is the largest organ in the body. In humans it is separated incompletely into lobes, covered on their external surfaces by a thin connective tissue capsule.
The eye is a small window to the body in itself. many systemic diseases can be diagnosed by carefully examining the eye. systemic disorders are associated with eye conditions that are either direct or indirect manifest the underlying disease process. On the ward, this may present in two ways: the patient may be known to have a general condition and is concurrently suffering from a related eye problem. Alternatively, and more rarely, a presenting eye problem may be the first indication of underlying systemic disease. Regarding liver diseases, nearly all parts of the eye can be affected, including orbit (frontal bossing and metastatic liver tumors to the orbit), eyelids (Xanthelasma), conjunctiva (Jaundice, Keratoconjunctivitis sicca and tear abnormalities), cornea (Wilson’s disease, pigmented peripheral corneal rings in non Wilson’s conditions and in Alagille’s syndrome and corneal arcus), Lens (galactosemia, Zellweger’s syndrome, cerebrotendinous xanthomatosis and Wilson’s disease), retina (Pigmentary retinopathy in systemic mucopolysaccharidoses, Zellweger’s cerebrohepatorenal syndrome, abetalipoproteinemia, Perimacular retinal deposits in sphingolipidoses, Perimacular retinal deposits in glycogen storage diseases and Wilson’s disease) and neuro-ophthalmologic manifestations (optic atrophy, Wernicke’s encephalopathy, Gaze palsies and oculomotor apraxia and Nystagmus).
HCV infection has been associated with several eye disorders. Keratoconjunctivitis sicca (dry eyes) is part of SS. Mooren’s ulcer is a rapidly progressive, painful ulceration of the cornea. The diagnosis is made by exclusion of other causes of corneal ulcer. A few cases of Mooren’s ulcer and HCV infection have been reported. In at least two of these patients, the ulcers did not respond to steroid and cyclosporine DROPs but did respond to interferon alfa-2b.
Ocular complications of interferon therapy have been widely observed. The most frequently occurring abnormalities are the appearance of cotton wool spots and/or retinal haemorrhages.
The incidence of ocular infections following kidney, heart, and bone marrow transplantations has been reported to vary between 2% and 5% and the incidence of ocular infections in orthotopic liver transplant patients was 1.3%. Fungal infections appeared earlier (mean, 42 days) than viral infections (mean, 128 days).