الفهرس | Only 14 pages are availabe for public view |
Abstract • MBG is a feasible and applicable method that has the advantage of simple ”on-line” determination of myocardial perfusion immediately after angioplasty in the catheterization laboratory, while still in the therapeutic window during which measures may be taken to improve a suboptimal result. • In addition to variable correlations with other perfusion markers at time of hospitalization among patients with acute STEMI, MBG showed a strong correlation with early (30-day) SPECT measures of myocardial perfusion, infarct size as well as left ventricular function (EF by echocardiogram) • In this study, MBG predicted myocardial viability detected in 30-day PCI SPECT study with a sensitivity of 96.8% and a specificity of 68.4%. • Despite our limited sample volume, our study showed that myocardial perfusion as assessed by MBG is positively correlated to LV function and myocardial viability. • The main finding of our study is that MBG after primary angioplasty for acute myocardial infarction is an important prognostic feature and should be added to the commonly used TIMI flow grading to define successful angiographic reperfusion with primary angioplasty for acute myocardial infarction. • Early and sustained restoration of flow into the infracted myocardium is the aim of reperfusion therapies for acute myocardial infarction. • Angiographic studies of reperfusion therapies should assess myocardial perfusion as well as flow in the epicardial infarct–related coronary artery. |