الفهرس | Only 14 pages are availabe for public view |
Abstract Antiphospholipid antibodies ( APAs), namely , lupus anticoaglant & anticardiolipin antibodies are acquired autoantibodies that can occur in many pathological conditions as connective tissue diseases ( S.L.E & Rheumatoid arthritis) & in infectious disease (acquired immunodeficieny syndrome , infectious mononucleosis & in chronic infections as leprosy ) as well as drug induced ( Fansidar , Hydralizine , Streptomycin , Quindine , Procainamide ) . Patients with APAs are prone to repeated episodes of both arterial & Venous thrombosis , Cardiomyopathy , thrombocytopenia , Fetal losses , renal failure , neurological & Skin manifestations . The primary antiphospholipid antibodies syndrome refers to the presence of the above dinical manifestations without evidence of an associated autoimmune disorders . conducted on 50 patients with cerebral ischemia ( Cerebral thrombosis , transient ischemic attacks ) as well as 15 healthy controls , patients were classified into 2 groups : - Group 1 : It included 30 patients ( 10 males & risk factor that can predispose to D.M , hyperlipoproteinemia .. etc .. The aim of our work is to shed light on the prevelance of APAs & the role played by these antibodies in cerebral ischemia . Our study was 20 females ) with no evidence of any cerebral ischemia e.g hypertension , |