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Abstract
Oral lichen planus is a common chronic immunologic inflammatory mucocutaneous disorder of unknown cause that varies in appearance from keratotic (reticular or plaque-like) to erythematous and ulcerative. It has a prevalence rate range between 0.1 and 2.2%, with a peak incidence in middle age patients and has female predominance of2:1.
The most commonly employed and useful agents for the treatment of oral lichen planus are topical corticosteroids. The addition of potent immunosuppressant or immunomodulatory agents such as cyclosporine, tacrolimus, pimecrolimus or tretinoin, in topical formulations, may be beneficial in this group of patients. Clobetasol, super-potent halogenated corticosteroid, is known to be probably one of the most effective drugs i