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Abstract This experiment was carried out at the Poultry Research Fann , belonging to Animal Production Department , Faculty of Agriculture, Zagazig University, Benha branch. The present study was aimed to evaluate the effect ofBio - Tonic (as herbal extraction) , Fermacto (as a natural feed supplement based upon a pnmary fermentation, Aspergillus), Kemzyme (as enzyme preparation containing alfa - amylase, protease , beta - gLucanase , lipase and cellulase) and Zinc bacitracin (as a poly peptide compound complex with stable Zinc) as feed additives, on productive performance and metabolic responces of broiler . A total number of 576 one - day old Hubbard broiler chicks were randomly distributed into 4 - main groups each of 144 chicks. Birds of each group were subdivided into four subgroups each of 36 chicks ( in three replicates of 12 chicks each . The main groups are received basal diets with 0.0 , 0.5 , 1.0 and 1.5 kg/ton ration of either Bio - Tonic, Fermacto , Kemzyme or Zinc bacitracin, respectively. The experimental chicks were raised under similar conditions of management, vaccination, heating and lightening. Chicks were individually weighed to the nearest (g) at the first week and at weekly intervals thereafter throughout the experimental period (lasting 7 weeks) . Weight gain between two successive weeks were individually calculated . Feed consumed by all chicks of each treatment was daily recorded, averaged and expressed in gram per chick during the periods from (0 - 4 , 4 - 7 and 0 - 7) weeks of chicks age. Feed conversion then calculated as a ratio between feed consumption and body weight gai.n . Keel and Shank lengths were individually measured after the end of the 1 st ,4 th and 7 th weeks of chicks age . Economic efficiency and Performance index was also calculated. Slaughter and carcass quality were measured at 51 day of chicks age. Serum total protein, albumin , globulin, A/G ratio, total lipids , cholesterol , GOT , GPT, alkaline phosphatase, uric: acid and creatinine were determined at 28 and 51 days of age . In addition tissues uric acid and creatinine were recorded at 51 day of age . The results obtained could be summarized as follows: 1- Body weight: a - Chicks fed diets containing Kemzyme increased body weight over those fed either Bio - Tonic, Fermacto or Zinc bacitracin by (23.2 , 47.0 and 5.9 g) , respectively at the end of the experimental period. Significant variation due to dietary levels applied was found on average body weight at 4 th and 7 th weeks of chicks age . b - Chicks fed a,s kg Bio -Tonic /ton ration had the highest average of body weight (1041.6 g) at the 4 th week. On the other hand, chicks fed 0.5 kg Zinc bacitracin lton ration had the highest average of body weight (2106.8 g) at the end of the experimental period when compared with other treatments applied . 2 - Body weight gain: a - Chicks fed Bio - Tonic showed the highest average of body weight gain at the period from (0 - 4) week of age. While those fed Kemzyme had the highest average at the periods from (4 - 7 and 0 - 7 ) weeks of chicks age . b - Supplemented diets with either 0.5 kg Zinc bacitracin or 1.5 kg Iton Kemzyme showed the highest body weight gain averages at the period from (0 - 7) Wk of chicks age, respectively. c - Highly significant effect due to supplemented levels was found on the average body weight gain during the periods from (0 - 4) and (0 - 7) wks only. 3 - Keel and Shank lengths : a - Dietary levels had highly significant variations on keel length at 7 th week only and shank length at 4 and 7 weeks of chicks age . b - Chicks received BiD - Tome increased Keel length at 1§1 and 7 th weeks . While those fed Zinc bacitracin increased Keel length at 4 th week only. c - Supplementing chicks with Kemzyme had the highest average of Shank length at all periods of estimation. d - Chicks fed 0.5 kg Bio - Tonic / ton ration showed the highest average of keel length at 7 ID week of chicks age. 4 - Feed consumption and Feed conversion: a - Chicks fed ration containing Zinc bacitracin showed the lowest average of feed consumption at all periods of estimation . b - Feeding chicks diet containing Zinc bacitracin had better value of feed conversion at all experimental periods , followed by those fed either Kemzyme or Bio - Tonic. c - Chicks fed 0.5 kg Zinc bacitracin / ton ration had the better average of feed conversion followed by those fed 0.5 kg Bio - Tonic / ton ration. d - Highly significant variations were found in feed conversion due to dietary levels applied . 5 - Economical efficiency and Performance index: a - Chicks received Bio - Tonic in their diet had the higher performance index at 4 th week of age ,followed by those fed diets with Kemzyme. On the other hand, feeding chicks diet containing Zinc bacitracin had the highest performance index at the end of the experimental period, followed by those fed Kemzyme , respectively . b - Chicks fed Zinc bacitracin had the highest average of economical efficiency allover the experimental periods followed by those fed Bio - Tonic. c - Feedins chicks on diet supplemented with O.S kg I ton ration of either Zinc bacitracin or Bio - Tonic ,respectively increased economic efficiency when compared with other levels of different treatments applied. 6 - Carcass characteristics : a - Chicks fed diet with Kemzyme had the highest absolute and proportional weights of eviscerated, giblets, total edible meat and decreased average of absolute and proportional weights of abdominal fat, followed by those fed diets containing Fennacto in absolute and proportional eviscerated weights and absolute weight of total edible meat . b - Significant variation in abdominal fat percentage and absolute and proportional weights of giblets were found due to treatments applied. However, significantly variations in eviscerated weight, abdominal fat, giblets and total edible meat were found due to dietary supplemented levels. c - Chicks fed 0.5 kg Zinc bacitracin or 1.0 Kg Kemzyme Iton ration, respectively increased significantly total edible meat when compared with other levels applied . d - Feeding chicks on diets containing Fermacto had the highest average of total protein in meat, followed by those fed Zinc bacitracin . While those fed diets with Bio - Tonic or Kemzyme had the lowest total protein value . e - Chicks fed Bio - Tonic decreased average of ether extract, moisture and ash of meat content. f - Highly significant variation in protein, ether extract and ash of meat content were found due to troatmenta applied. 7 - Serum blood parameters: a - Highly significant variations were found in serum total protein , albumin , globulin ,A/G ratio , total lipids , cholesterol , alkaline phosphatase , GOT , GPT , uric acid and creatinine at 28 and 51 day of age due to treatments applied . Similar results were observed in tissues uric acid and creatinine . b - Feeding chicks diets containing Bio - Tonic decreased average of serum creatinine , total lipids and cholesterol and increased serum alkaline phosphatase and GOT at 28 day of chicks age . While at 51 day of age , chicks fed Bio - Tonic had the lowest average of serum uric acid, creatinine , total lipids , cholesterol and tissues uric acid and creatinine . c - Chicks fed Fennacto showed the lowest average of serum uric acid and highest average of serum total protein and globulin at 28 day of chicks age . While at 51 day of age , these chicks decreased average of total lipids and increased average of serum total protein and globulin . d - Feeding chicks diets containing Kemzyrne had the highest average of serum albumin , A/G ratio and OPT at 51 day of chicks age only. e - Chicks received diets containing 1.5 kg Fermacto / ton ration showed the highest averages of serum total protein and albumin at 51 day of age . f - Chicks fed 0.5 kg Kemzyme / ton ration had the highest average of serum alkaline phosphatase at 51 day of age. WhiJle, chicks fed 1.5 kg / ton Bio - Tonic and non - supplemented control diet had tho highest averages of serum GOT and OPT at the same age. g _ Feeding chicks diet containing 1.5 kg Bio - Tonic / ton ration significantly decreased serum and tissues creatinine and tissues uric acid content when compared with other levels of different treatments applied . 8 - Digestible coefficient, TDN and Nitrogen balance: a - Feeding chicks diets containing 0.5 Kg/ton Zinc bacitracin had the higher crude fiber digestibility . While the highest average of fat digestibility coefficient was found in chicks fed 1.0 kg/ton Fermacto . b - Chicks fed 1.0 kg/ton Kemzyme had the highest average of crude protein digestibility. While those of control groups had the highest nitrogen free extract and organic matter digestibility. c - Chicks of control groups had the highest average of total digestible nutrients (TDN) . d - Feeding chicks with 1.5 kg/ton Zinc baciracin had the highest average of nitrogen balance, followed by those fed 0.:5 kg/ton Kemzyme . 9 - Mortality rate: a - Chicks fed diet containing Kemzyme or Zinc bacitracin decreased mortality rate. While those fed Fermacto had the highest average of mortality rate . * Generally) it can be advised to supplement broiler diets with 0.5 kg / ton of either Zinc bIOitraein or Bio - Tonic in order to get higher economical efficiency . |