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Abstract Summary studies on fatty liver syndrome in laying hens and associated bacterial agents. For e/LucFyl nj the mci riEnce of ewposure of 1 ayi nq hens reared hatter j es j ri Fen:i —9uef , El —Men i a and - ñE>si ut Governor- at es to att:y I i vc-r- syndrome anci a cD{ri a.ted bacterial agen±s. 00 fresFil y (J&!acr b.i r ds were stAbj ec:tE.-?c! t.r.D P. Ii. exami [Na 1i on from Lh1 ch 100 hi rd ]1 ow& 3 1 as i on cs of 4 at: t y 1 1 ver- syndrome. 2- P 1, €? x am i nat i cr3 s Bh owed a CC U T,Li 1 at i a of fat i n the cF c)m i nat cavity and liver as qreesy in texture, en] arged, yell cv” sh in cci cr and ir-i abi e, In scmEr c:ases, liver was ccver<c[ i th a ) ay€,r cf C: 1 ctt.ed bi cod resul teci 4rorn riApture of 11 ver — -- 13acter ol ogi cal cx arni nations -f or 10(1 freshly dead hi rds I ccl to I so I. at ± On ci f 90 so 1 ate 4 tuj orhemi cal and morphrfl ogi cal rherect.ers of the I sd ates 1. ndi crat.ed i sd at i on cf U2.) EEJ ccli i sd ates, ( Sal rriorel Ia 1 sd atE?es • é) Prc,t.eus mi raba ii s, (4) ertrotje.c ter and (5) ki ebsi ella organisms. 5— F-li stop at h ci oj I c: a 1 exam i nat :i. on s showed fat. t y d eq en Er at ion cf hepati C: cells in twr forms-, fatty degenerati on of hE’pat.i c cells without necrotic c:hanges or cci.] Lii ar reacti orts and fatty dec}enc-rati or. of hepati C tel 1s with Cell Li] ar reacti r,ns &-- FLB was Experl iTi1..r:ta:L 1 y ± ndLLced by r3j ecti on of estrogen or acrd It ran 01: Ki in Iced or i nj ert,. nrl of cstrcqen arid addi ti on of 1< I. 7-- The rEL-:ui t i ncr) cat&d that, I I cecti cr of estrcicgz•n .3 addi ti on of F] s the best method fc:’r induction of the syndr Oir’c Cr per i mental 1 y as mani 4-ted by F. M . pathol og:i ca) r- cLur e and cicot.t.r rcii 1 at i cri Su: C: (?ssfu1 t.rj a] s for tr trnyr1t. o+ th yridrpmE Wr e madE by ng cr.pr.er ( i —ni cr,t,.ni C: act d cop c or tiSi ncj Dc vi tarri fl. r3€:r—al. and arLi nb ac:i ci mix t.ur—e at i ndi rated vñ th P 3 .i ver El h t irt d path ci cq ± cal p i C: t u r € vh I ci, e near .1 y ri C, r ma 1 reiltmc,nt el so 1. E’d tci i. rnprovecl liver fur!crt.: j. Ofl 6 Ir]eaUrEd by s(er LU 6]T |