الفهرس | Only 14 pages are availabe for public view |
Abstract Aim of the work To study serum levels of IL-6 and TPO in thrombocytopenic neonates, to detect if they have a role in thrombopoiesis and their value in diagnosis of severity of thrombocytopenia. In conclusion, neonatal thrombocytopenia remains a common clinical problem. Fortunately most episodes of thrombocytopenia are mild or moderate and resolve spontaneously without apparent clinical sequelae. For more severe episodes the recent demonstration of impaired megakaryocytopoiesis and platelet production, as a major contributor to neonatal thrombocytopenias is a major advance both in terms of mechanistic accuracy and the potential therapies. |