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Abstract
Chronic liver diseases often begin with the anatomic clinical state of chronic hepatitis and can evolve to liver cirrhosis and hepatocellular carcinoma. Chronic hepatitis attributable to hepatitis virus C ”HCV” is the entity that most frequently evolves to liver cirrhosis (Fortunato et al., 2001).
HCV infection is a major public health problem all over the world with a global prevalence of 3% (170 million of infected), with 3-4 million people being newly infected each year (WHO, 2000). Egypt has the highest prevalence of adult HCV infection in the world, averaging 15%-25% in rural communities (El-Raziky et al., 2007).
In the majority of patients, chronic HCV infection is a silent disease until significant hepatic fibrosis. Chronic hepatitis C infection results in damage to hepatocytes and may eventually lead to liver fibrosis, cirrhosis and / or hepatocellular carcinoma (Shen et al., 2006).
One of the most important actions to prevent the un-controlled