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Abstract Six difj”erent five- membered cycljc (-substituted 22methoxy-l,J,2- oxazaphospholidine-2-sulfidee ~e re pyntheeeized from the reaction of six different DC -aminoelcohole ~ith methyl O-(J-methyl-4-nitrophenyl)phosphorochloridothionate which was obtained in a pure state from Sumitomo Chemical Co., 1- 0:: -Aminoalcohols: Glycine, Lysine, cysteine, glutamine, hi~tidine and phenylalanine were firstly esterified(methylester) then reeduced with sodium borohydride to give in corresponding cCalcohol. After purification of Cf:- -amino alcohels with d istilllation or recrystelization, their physical constants such as boiling point, melting point and Rf values in different sollvent systems were determined. Elementary analysis and IR;H-1T1iR spectra confirmed their chemical structures. Six different 4idine 2-sulfides were prepared by different co~binations of the corresponding aminoalcohols and O-methyl-O-(J-methyl 4phenyl) phosphorochloridothionate. The products were purified by using column chromatography and then with recrystalization. Their melting-point, Hf values end molecular formulas from elementary an&lysis were determined. |