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العنوان
Synthesis and Biological Activity of some New Organic Compounds /
المؤلف
Gobrail, Magdy Yacoub.
هيئة الاعداد
باحث / Magdy Yacoub Gobrail
مشرف / A.H. El-Sayed
مشرف / Mohamadt A. Issa
مشرف / Salah M. Abdel-Kader
مشرف / Zidan Z.H
الموضوع
Agricultural chemistry. Biochemistry.
تاريخ النشر
1991.
عدد الصفحات
58 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الزراعية والعلوم البيولوجية (المتنوعة)
تاريخ الإجازة
1/1/1991
مكان الإجازة
جامعة المنيا - كلية الزراعة - قسم الكيمياء الحيوية
الفهرس
Only 14 pages are availabe for public view

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Abstract

Six difj”erent five- membered cycljc (-substituted 22methoxy-l,J,2- oxazaphospholidine-2-sulfidee ~e re pyntheeeized from the reaction of six different DC -aminoelcohole
~ith methyl O-(J-methyl-4-nitrophenyl)phosphorochloridothionate which was obtained in a pure state from Sumitomo Chemical Co.,
1- 0:: -Aminoalcohols:
Glycine, Lysine, cysteine, glutamine, hi~tidine and phenylalanine were firstly esterified(methylester) then reeduced with sodium borohydride to give in corresponding cCalcohol. After purification of Cf:- -amino alcohels with d istilllation or recrystelization, their physical constants such as boiling point, melting point and Rf values in different sollvent systems were determined. Elementary analysis and IR;H-1T1iR spectra confirmed their chemical structures.
Six different 4idine 2-sulfides were prepared by different co~binations of
the corresponding aminoalcohols and O-methyl-O-(J-methyl 4phenyl) phosphorochloridothionate. The products were purified
by using column chromatography and then with recrystalization. Their melting-point, Hf values end molecular formulas from elementary an&lysis were determined.