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Abstract Pulmonary hypertension is a common complication of chronic obstructive pulmonary disease COPD. Pulmonary hypertension in COPD is generally limited to an increase in mean pulmonary artery pressure to 25-35 mm Hg. Pulmonary hypertension (PH) is an important predictor of mortality in chronic obstructive pulmonary disease (COPD) . The phosphodiesterase 5 inhibitor sildenafil has been demonstrated to reduce pulmonary arterial pressure (PAP) in different diseases. Our aim was to investigate the effect of sildenafil on echocardiographically estimated PAP and its impact on the weaning of patients with acute exacerbations of COPD. Pulmonary hypertension PH is an important predictor of |