الفهرس 
Introduction and aim oldie workOnly 14 pages are availabe for public view
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Abstract
Aim of the work
To study the effects of ANH on hemodynamics, hematological parameters, acid base status and serum electrolytes and to study the effect of ANH to minimizing the requirements and use of homologous blood transfusion.
Summary and conclusions
In this study the patients were randomized into two groups: study group (exposed to ANH) in which one liter of blood was withdrawn over 40 minutes to be replaced at lower allowable hematocrit (21%) and control group which is exposed to homologous blood transfusion.
Hemodilution caused a decrease in hematocrite and hemoglobin but HR and mean arterial blood pressure, acid base parameters and serum sodium and potassium were stable or insignificantly affected.
Hemodilution of patients to a mean hematocrite 31.3 +(-)2.1% as well as tolerated and the extend of the dilution by surgical blood loss to a mean value of 24.8+(-)2.4% without significant effects except simple extend for the normal response, while the impact of anesthesia in modulating this effect can not be omitted and needs more investigations. Also, the results of this study showed the safety of the technique and validity as blood conservation method.
In conclusion ANH is considered as a safety technique in the suitable patients fulfills the inclusion criteria plotted for the study.
Hemodilution of the patients to a mean hematocrite value 0f 31.3 or extend of hemodilution by surgical blood loss to a mean hematocrite value of 24.8 was well tolerated in those patients.
Hemodilution significantly decreased the need for homologous blood transfusion in major elective major surgery.
Clinically, severe degrees of hemodilution than previously reported may be acceptable but it needs further studies may be accepted but it needs further studies for evaluation.