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Abstract Summary A total number of 145 affected lungs (121 sheep and 24 goats), 14 affected trachea (9 sheep and 5 goats) and 10 affected heads showed signs of respiratory tract infection were collected out of 1250 examined animals (1000 sheep and 250 goats) from December 2003 to December 2004. The specimens were collected from El-Monieb, El-Arish, El-Suez slaughter houses as well as from the farm of the Faculty of Agriculture, Suez Canal University. Pasteurella spp. were isolated from the upper and lower respiratory tissue (63 sheep and 25 goats). Corynebacterium spp. were isolated from the lung of 29 sheep. Staphylococcus aureus was isolated from 16 sheep and 2 goats. Streptococus pneumoniae was isolated from the lung of 4 affected sheep. E. coli was isolated from the pulmonary tissue of 11 sheep and 3 goats. Proteus spp. were isolated from the lung of 4 affected sheep. Parasitic infections were detected in 7 affected sheep (4 were lung worm and 3 were Oestrus ovis). Cryptococcus spp., pulmonary adenomatosis, nasal polyp, foreign body rhinitis and foreign body pneumonia were observed in one animal each. Various affections were observed in the upper respiratory tract. Pasteurella haemolytica was isolated as a single infection or mixed with Staphylococcus aureus. Several developmental stages of Oestrus ovis were detected in the upper respiratory tract of 3 affected sheep that exhibited respiratory manifestations and sometimes-nervous manifestations. A case of nasal polyp was seen in one affected sheep that showed severe dyspnea. A case of foreign body rhnitis was detected in a nasal cavity of a sheep. • Lower respiratory tract showed various affections. Pasteurella spp. was the most prevalent pathogens in the lower respiratory affections. It induced severe pathological alterations either in single infection or in association with other pathogens. The course of the disease was also variable ranging from the acute, subacute to the chronic form. Grossly, different stages of pneumonia and grayish areas of necrosis were seen. Microscopically, different types of pneumonia, necrosis and oat cells were seen. Corynebacterium infection resulted in grayish-white nodules, that were concentrically lamellated in cross section. Microscopically, pyogranulomas contained bacterial colonies were observed. Staphylococcus infection was observed in two forms, acute and chronic. Streptococcus infection caused hemorrhages within the alveoli. Other. bacterial infections (E. coli &Proteus spp.) induced bronchopneumonia and/or interstitial pneumonia. Parasitic infection was observed as nodules within the diaphragmatic lobe and appeared microscopically in acute form with interstitial pneumonia and Chronic form with granuloma formation. Mycotic pneumonia was observed grossly as small nodules in the cranioventeral portion of the lung. Microscopically, multiple granuloma contained several yeast cells. Pulmonary adenomatosis, which exhibited proliferative lesion of alveolar epithelium. Foreign body (needle) was found in a lung of sheep in a canal and surrounded with massive fibrosis. • |