الفهرس | Only 14 pages are availabe for public view |
Abstract The purpose of the present study is to evaluate the changes in the compliance of the respiratory system and airway resistance in mechanically ventilated patients with acute respiratory failure due to pulmonary diseases particularly neurological diseases and chest wall disorders. Value of monitoring respiratory mechanics particularly static and dynamic compliance and also airway resistance as a part of weaning parameters, this in addition to follow up changes in arterial blood gases before and after the disconnection of mechanical ventilation. From the study we conclude that: Measurement of the total static compliance is peripheral to dynamic compliance for assessment of the pulmonary changes. Initial values of respiratory mechanics and arterial blood gases in our study have no predictive value for weaning success or failure. The continuous monitoring of compliance especially static compliance can be percussive in predicting the start of weaning, so patients who were successfully weaned showed a significant improvement in the form of increasing in both static and dynamic compliance and reducing airway resistance. Airway resistance was a less important factor in patients with extra pulmonary disease. Measurements of compliance and resistance can provide more complete evaluation of the effect of therapy in mechanically ventilated patients. All patients who received MV for drug over dose and most patients with cardiogenic pulmonary edema were successfully weaned, while all patients with ARDS and cerbrovascular stroke were failed in weaning. After weaning ABGs analysis leveled their values in the survivors of extra pulmonary diseases (mainly due to drug over dose or kyphoscelosis) were better especially for PaO2 and PaCO2 which was lower than in pulmonary groups. |